Latisse use may also cause darkening of the eyelid skin which may be reversible in most patients. It is possible for hair growth to occur in other areas of your skin that Latisse frequently touches. Any excess solution outside the upper eyelid margin should be blotted with a tissue or other absorbent material to reduce the chance this from happening. Latisse solution is intended for use on the skin of the upper eyelid margins at the base of the eyelashes. Refer to illustration 2 below. DO NOT APPLY to lower eyelid.